Clinical Pharmacology Chapter 15 Antipsychotics Q&A (1 OF 28) Sample Questions

1. Which of the following antipsychotics is the least sedating?
  1. A. Clozapine
  2. B. Haloperidol
  3. C. Olanzapine
  4. D. Risperidone
  5. E. Chlorpromazine
Answer
Ans: B
Tips: CTC. Psychoses Chapter. Low-potency first generation antipsychotics (chlorpromazine) and second generation antipsychotics (clozapine, olanzapine & Risperidone) are more sedating compared to high-potency FGA like haloperidol. High-potency FGAs however have greater rates of EPS, NMS and elevated prolactin levels.